NC Researchers Fighting Honey Bee Extinction with New Technology

RALEIGH, N.C. (September 5, 2025) — A pesky parasite is impacting bees, threatening colonies all over the world.

Bees keep our crops pollinated and now their keepers are looking for a way to stop this killer. Honey bees are a key contributor in the state’s largest industry.

“Part of our goal really is shoring up food security, crop production in North Carolina,” said Kaira Wagoner, a research scientist at UNC Greensboro works in the UNCG Plant & Pollinator Lab located at Gateway Research Park in Greensboro, North Carolina.

Wagoner and her team are keeping the buzz about bees going from the honeycomb to the fume hoods.  Wagoner’s passion is protecting one of the planet’s most prolific pollinators.

Researchers have pinpointed the parasite responsible for decimating bee colonies across the country.

The Varroa destructor, a small mite that’s living up to its name, is feeding on honey bees and amplifying deadly viruses, Wagoner said.  “That’s really the No. 1 threat to honey bee health in the United States, and really globally, is this mite and the damage that it causes through spreading of those diseases,” she said.  These sly creatures bury themselves in brood cells, the small hexagonal openings in the hive, where bee pupa are developing.

“She hides under that food and has a snorkel to breathe,” Wagoner said. “They cap over that cell so she can’t be detected as easily. Then the baby bee will eat up that food, releasing her from that brood food. She’ll come out and start feeding on the baby.”

Wagoner said some bees have a way of stopping the spread.

“The honey bees that can smell very well, that are very sensitive, can then detect these Varroa mites, these problems, and throw them out of the colony, preventing the colony from dying,” Wagoner said.

Wagoner developed a method to find these overly hygienic bees so they can be used for future breeding.

Her technology is called unhealthy brood odor or UBeeO. The pheromone-based spray mimics the scent of a Varroa mite. Once it’s on the frame, it’s placed back in the beehive. Two hours later the same frame is removed, examined and photographed to document the progress.  The tests we saw had mixed results.

The first frames were mostly untouched, and this hive didn’t uncap any cells.  A second set of bees removed a few, even pulling out some of the pupa to prevent potential spread and look for mites.  The final test we watched had near perfect results.  The bees checked every sprayed cell.

Wagoner says colonies that can identify at least 60% of the sprayed cells have fewer mites, less bacteria and lower fungal loads.

High-scoring colonies are also found to have fewer viruses, all qualities that make them good candidates for selective breeding, a process intended to strengthen bees.

Wagoner is exploring another discovery using NCInnovation funding from the state.

She found hygienic honey bees have a different microbiota from less-hygienic bees.  Her team of researchers is now exploring that link. “We have potential to develop a product out of this, finding that could actually improve honey bee health,” Wagoner said. “We’re starting to get into that in the last few years and we have a lot of exciting research ahead of us, thanks to NCInnovation.”

Wagoner said beekeepers from all over the world are interested in her research and starting to use UBeeO for themselves to identify hygienic bees.  She hopes her technology can promote more intentional breeding that can help bees be more resistant to parasites and save farmers money by eliminating the need for expensive miticides.

Plant & Pollinator Center Receives Funding from the Dorothy Levis Munroe Research Fund

GREENSBORO, NC – JUNE 13, 2024 – In the 2023-24 academic year, the College of Arts & Sciences Office of Research supported 20 UNCG students with nearly $20,000 in grants from the Dorothy Levis Munroe Research Fund. The fund was endowed by alumna Dorothy Levis Munroe ‘44 to support student research in the “natural and mathematical sciences.”

All 20 students conducted research in STEM departments: twelve in Biology, four in Chemistry and Biochemistry, two in Computer Science, and one each in Mathematics and Nanoscience. Students won support by submitting a research proposal and project budget up to $1000, depending on their project needs. Five Munroe grant recipients were undergraduate students, fourteen were graduate students, and one was a post-bacc student.

The list of items purchased with Munroe funds shows the diversity of research undertaken by these student scientists. They used award funds to purchase:

  • 250 Pine seedlings, 144 bluestem grass plugs, potting soil, and pots
  • Dissecting scissors, nets, an aquarium bubbler, and a heavy-duty wagon to haul these and other tools needed for collecting and tagging fish in streams across central NC
  • Carbon nanotubes to study DNA uptake of duckweed
  • Fluorescent Yellow Particles and Fetal Bovine Serum for research into the uptake of microplastics by human endothelial cells, which line the inside of our blood vessels.
  • Kits for genetic analysis in experiments with the drought-resistant grain tef
  • Chemical reagents and organic solvents
  • Lab supplies such as Erlenmeyer Flasks and well plates.

Munroe grants also supported travel by students to conduct research and attend conferences and scientific meetings. Their work took them to places near and far, including:

  • Fieldwork in Morganton and Elizabeth City, NC to study the ecology of chigger mites.
  • Fieldwork in South Africa’s Kruger National Park to study the effects of drought, fire, and extreme grazing on grasslands.
  • Fieldwork in the Gateway Research Park and at UNCG’s Plant and Pollinator Center.  The UNCG Plant & Pollinator is located at the 75-acre Gateway Research Park located on Summit Avenue in northeast Greensboro.  
  • Fieldwork at the Konza Prairie Biological Station in Kansas to study grassland recovery following nitrogen cessation in areas previously subject to chronic nitrogen addition.
  • NVIDIA’s GTC 2024, one of the top Artificial Intelligence conferences, to gain insights to improve a project developing new processes for clinical trial recruitment.
  • The Wildlife Society’s annual conference, to present a poster on phylogeography and flea community ecology of the long-tailed ground squirrel.
  • The International Computing and Combinatorics Conference, to share a paper titled “Improved Sourcewise Roundtrip Spanners with Constant Stretch.”
  • The Joint Mathematics Meetings, to share mathematical research into ecological models of species interactions.
  • The North Carolina Academy of Science annual meeting, where the student won the John Bowley Derieux Research Award.

Many of the students also participated in UNC Greensboro’s Graduate Research & Creativity Showcase of Scholarship or in the Thomas Undergraduate Research & Creativity Expo, where they presented posters or gave oral presentations.

Dorothy Levis Munroe graduated as a chemistry major from UNCG in 1944, along with her twin sister Katheryne Levis McCormick. Munroe went on to earn a master’s in chemistry, teach high school mathematics for many years, and become the first woman to serve on the board of education in Newark, Delaware. By endowing this fund at UNCG, Munroe hoped to encourage students to pursue the sciences by providing resources for their research.

Source:  UNCG Office of Research and Engagement
https://research.uncg.edu/